Concept & Clues WARNING: SLIDES CONTAIN GRAFIC IMAGES SUTIABLE FOR MEDICAL STUDENTS STUDYING FOR STEPS. NOT INTENDED FOR ANYONE ELSE. ALSO THE PICTURES TAKEN BY YAHOO IMAGES AND VARIOUS OTHER SITES IF ANYONE HAS PROBLEM REGARDING PICTURES PLEASE POST COMMENT AND WE WILL REMOVE IT IMEDIATELY. ITS FOR TEACHING PURPOSES ONLY conceptclues.blogspot.com 1

What are the 5 bacteria causing heart block conceptclues.blogspot.com 2 L yme disease Salmonella typhii (typhoid) Chagas Disease (whipple’s) Legionella Diptheria Acronym: Long Sex Causes Low Diet

What bacteria causes Reiter’s Syndrome S higella I BD (Crohns) Y ersina C hlamydia Acronym: She Ickies YC 3 conceptclues.blogspot.com

What R the low compliment bug causing cryoglobuniemia I AM HE Influenza Adenovirus Mycoplasma Hepatitis C EBV(epstein barr virus) 4 conceptclues.blogspot.com

What are the drugs that blast the bone marrow AZT Benzene Chloramphenicol Vinblastine 5 conceptclues.blogspot.com

What are the drugs induced SLE ACRONYM: HIPPE Hydralazine INH Phenytoin Procainamide Penicillamine Ethosuximide 6 conceptclues.blogspot.com

What are the comma shaped bugs Vibrio Campylobacter Listeria H.pylori VICTOR CAME LUSTING HOPEFULLY 7 conceptclues.blogspot.com

What is cresent shaped protozoa Giardia Lamblis 8 conceptclues.blogspot.com

What bacteria looks like chinese letters 9 conceptclues.blogspot.com Corynebacter

What are the TB reaction RESPI Rifampin Ethambutanol Streptomycin Pyrazinamide Isoniazid 10 conceptclues.blogspot.com

what are the 6 low complement a/w neprotic syndrome Serum Sickness PSGN (poststrep glomerulonephritis) SLE SBE (Subacute Bacterial Endocarditis) Cryoglobinemia MPGN II 11 conceptclues.blogspot.com

What are the drugs that induce or inhibit p450 Induce BAG-CR-QTS Barbituates Alcohol Griseofulvin Carbamazapine Rifampin Quinidine Tetracycline Sulfa drugs Inhibit I D SMACK QUINOLO Isoniazid Dapsone Spironolactones Macrolides Amiodarone Cimentidine Ketoconazole Quinolones 12 conceptclues.blogspot.com

What drugs are p450 dependent WEPT-D Warfarin Estrogen Phenytoin Theophylline Digoxin 13 conceptclues.blogspot.com

What disease is a Neutrophil Definiciency CGD = chronic granulomatous disease AKA: NADPH Oxidase Deficiency 14 conceptclues.blogspot.com

What are the side effects of statins HIM Hepatits Myositis Increased liver enzymes 15 conceptclues.blogspot.com

What are the painful genital lesions? Chancroid Herpes Lymphogranuloma Inguinale 16 conceptclues.blogspot.com

What bacteria causes painful chancroid lesion Haemophilus Ducreyi 17 conceptclues.blogspot.com

What are the 4 hormones with disulfide bonds PIIG Prolactin Insulin Inhibin Growth Hormone 18 conceptclues.blogspot.com

What are the Hookworms? NEAT-AS Necatur Americanis Enterobius Vermicularis Ankylostoma Duodenale Trichuris Trichurium Ascaris Lumbercoides Strongyloides 19 conceptclues.blogspot.com

What are the X-Linked enzyme deficiencies? G6PD = glucose 6 phosphate dehydrogenase CGD = chronic granulomatous disease Pyruvate dehydrogenase deficiency Fabry’s Hunter’s Lesch-Nyhan 20 conceptclues.blogspot.com

What disease do we screen for at birth Please – PKU (phenylketouria) Check – CAH (congenital adrenal hyperplaisa) Before – Biotinidase Going – Galactosemia Home - Hypothyroidism 21 conceptclues.blogspot.com

HLA ANTIGENS 22 conceptclues.blogspot.com

HLA-DR2 Narcolepsy Allergy Goodpastures MS = multiple sclerosis 23 conceptclues.blogspot.com

HLA-DR3 DM = diabetes mellitus Chronic active hepatitis Sjogren’s SLE Celiac sprue 24 conceptclues.blogspot.com

HLA DR3 & DR4 IDDM (TYPE 1) 25 conceptclues.blogspot.com

HLA DR4 PEMPHIGUS VULGARIS RHEUMATOID ARTHRITIS 26 conceptclues.blogspot.com

HLA-DR5 Juvenile Rhematoid Arthritis Pernicious Anemia 27 conceptclues.blogspot.com

HLA-DR7 NEPHROTIC SYNDROME (steroid induced) Note: The common side effects of steroids are : hypertension, hypergylcemia, cushing features, hepatomegaly, osteoporosis, myopathay and cataracts. Hypertension, hyperglycemia and hepatomegaly are seen within the first 4 weeks of 2mg/kg of steroids in Nephrotic syndrome. Osteoporosis, cataracts and myopathy appear later. Screening for these is required if a child is a steroid dependent or a frequently relpasing nephrotic syndrome. A yearly Xray spine or DEXA scan, ophthal evaluation for catarct and Gowers test for myopathy are recommended. 28 conceptclues.blogspot.com

HLA-DR 3 & B8 CELIAC DISEASE 29 conceptclues.blogspot.com

HLA-A3 Hemochromatosis chromosome 6 point mutation: from cystine to tyrosine 30 conceptclues.blogspot.com

HLA-B8 MG = Myasthenia Gravis 31 conceptclues.blogspot.com

HLA-B27 Psoriais (only w/ arthritis) ankylosing spondylitis IBD Reiters Postgonococcal Arthritis 32 conceptclues.blogspot.com

HLA-BW 47 21 alpha hydroxylase deficiency (vit D) 33 conceptclues.blogspot.com

What are the actions of steroids KIISS Kills helper T- cells & eosinophils Inhibits Macrophage migration Inhibits Phospholipase A Stimulates Protein Syntheis Stabilizes Endothelium 34 conceptclues.blogspot.com

What are the causes of Monocytosis STELS Salmonella (typhoid) TB EBV Listeria Syphillis 35 conceptclues.blogspot.com

E.Coli is the most common cause of what? UTI Spontaneous Bacterial Peritonitis Abdominal Abscess Cholecystitis Ascending Cholangitis Appendicitis 36 conceptclues.blogspot.com

What are the one dose treatment for Gonorrhea Ceftriaxone Cefixime Cefoxine Ciprofloxacin Oflaxacin Gatifolxacin 37 conceptclues.blogspot.com

Gonorrhea image 38 conceptclues.blogspot.com

What is the one dose treatment for Chlamydia Azithromycin 39 conceptclues.blogspot.com

What are the “Big Mama” anaerobes Strep Bovis Clostridium Melanogosepticus Bacteriodes Fragilis 40 conceptclues.blogspot.com

Drugs that treat big mama anaerobes Clindamycin Metranidazole Cefoxitin 41 conceptclues.blogspot.com

What big mama bugs are a/w colon cancer Strep bovis Clostridium melanogosepticus 42 conceptclues.blogspot.com

What do u see in the serum w/ low volume state DECREASES K+ = decreases Na+ = decreases Cl- = decreases INCREASES pH = increases BP = increases 43 conceptclues.blogspot.com

What are psammoma bodies Calcified cancer 44 conceptclues.blogspot.com

In what diseases are pasmmoma bodies present Papillary carcinoma of the thyroid Serous cystadenomacarcinoma Meningioma Mesothelioma 45 conceptclues.blogspot.com

What are Urease+ bacteria PPUNCH Proteus Psudomonas Ureaplasma Urealyticum Nocardia species Cryptococcus neoformans H. pylori 46 conceptclues.blogspot.com

What type of stones are formed from proteus? Struvite (90%) Motility = swarming 47 conceptclues.blogspot.com

What are the 5 indication of Surgery IHOP Intractable pain Hemorrhage (massive) Obstruction (from scarring) Perforation 48 conceptclues.blogspot.com

Drugs that cause Cardiac Fibrosis Adriamycin (Doxyrubicin) Phen-fen 49 conceptclues.blogspot.com

What drug is used to treat cardiac fibrosis? Dozaroxsin 50 conceptclues.blogspot.com

What is the most common cause of any __ - penia? #1. virus #2. Drugs 51 conceptclues.blogspot.com

What is seen in the salmonella triad? High fever Rose Spots rash Intestina fire 52 conceptclues.blogspot.com High Fever Rose Spots rash Intestinal spots

What drugs cause myositis? RIPS Rifampin INH Predinsone Statins 53 conceptclues.blogspot.com

What are the 7 G- encapsulated bacteria Some = Salmonella Strange = Strep pneumo gr + Killers = Klebsiella Have = H.Influenza Pretty = Pseudomonas Nice = Neisseria Capsules = Cryptococcus 54 conceptclues.blogspot.com

What is the jones criteria for rhematic fever Sub Q nodules Polyarthritis Erythema marginatum Carditis Chorea 55 conceptclues.blogspot.com

What are the causes of Eosinophilla? NAAACP Neoplasms Allergies Asthma Addisons’s Disease Collagen vascular Disease Parasites 56 conceptclues.blogspot.com

What are the risk factors for liver cancer? Hep B,C,D Aflatoxin Vinyl Chloride Ethanol Carbon Tetracholoride Anyline Dyes Smoking Hemochromatosis Benzene Schistomiasis 57 conceptclues.blogspot.com

What are the 9 live vaccines Measles Mumps Rubella Oral Polio (sabin) Rotavirus Small pox BCG Yellow Fever Varicella 58 conceptclues.blogspot.com

What are the killed vaccines SIR-HEP A Salk ( polio) Influenza Rubella Hepatitis A 59 conceptclues.blogspot.com

What are the IgA Nephropathies Henosh-Schoenlein P (HSP) Alport’s Berger’s 60 conceptclues.blogspot.com

What are the drugs that cause autoimmune hemolytic anemia PCN Alpha-methyldoba Cephalosporins Sulfa PTU Anti-malarials Dapsone 61 conceptclues.blogspot.com

What are the drugs that cause autoimmune thrombocytopenia ASA (aspirin) Heparin Quinidine 62 conceptclues.blogspot.com

What are the enzymes that show after an MI? Troponin I CKMB LDH 63 conceptclues.blogspot.com

What is the first MI enzyme to appear Troponin I Appears = 2 hours Peaks = 2 days Gone = 7 days 64 conceptclues.blogspot.com

What is the 2nd MI enzyme to appear CK-MB Appears = 6 hours Peaks = 12 hours Gone = 24 hours 65 conceptclues.blogspot.com

What is the 3rd MI enzyme to appear LDH Appears = 1 day Peaks = 2 days Gone = 3 days 66 conceptclues.blogspot.com

What bacteria have Silver Stains Legionella Pneumocysitis carinii H.pylori Bartonella henseslae (lymph node) Candida (yeast) 67 conceptclues.blogspot.com

What are the sulfa containing drugs Sulfonamides Sulfonylurea celebrex 68 conceptclues.blogspot.com